A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath. it is caused by the release of cytokines from the cells that are targeted by the antibodies. most patients experience a mild to moderate reaction; however, the reaction may be severe and life-threatening. check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/c78251" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/conceptreport.jsp?dictionary=nci%20thesaurus&code=c78251" nci thesaurus)

In immunology, cytokine release syndrome (CRS) is a form of systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors such as infections and certain drugs. It refers to cytokine storm syndromes (CSS) and occurs when large numbers of white blood cells are activated and release inflammatory cytokines, which in turn activate yet more white blood cells...